Pharmacokinetics of the Melanocortin Type 1 Receptor Agonist PL8177 After Subcutaneous Administration

BACKGROUND AND OBJECTIVE: PL8177 is a selective melanocortin 1 receptor agonist in development for the treatment of various immunologic and inflammatory conditions. Here we describe the pharmacokinetics of PL8177 after subcutaneous (sc) delivery in animals and humans. METHODS: Mice, rats, and dogs w...

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Detalles Bibliográficos
Autores principales: Dodd, John, Jordan, Robert, Makhlina, Marie, Pesco Koplowitz, Luana, Koplowitz, Barry, Barnett, Keith, Yang, Wei H., Spana, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602434/
https://www.ncbi.nlm.nih.gov/pubmed/34693509
http://dx.doi.org/10.1007/s40268-021-00367-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602434/
https://www.ncbi.nlm.nih.gov/pubmed/34693509
http://dx.doi.org/10.1007/s40268-021-00367-y

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