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Inhibition of DTYMK significantly restrains the growth of HCC and increases sensitivity to oxaliplatin

Most patients with hepatocellular carcinoma (HCC) are in the middle or advanced stage at the time of diagnosis, and the therapeutic effect is limited. Therefore, this study aimed to verify whether deoxythymidylate kinase (DTYMK) increased in HCC and was an effective therapeutic target in HCC. The fi...

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Detalles Bibliográficos
Autores principales: Sun, Fengze, Liu, Yuanyuan, Gong, Tingting, Pan, Qiuzhong, Xiang, Tong, Zhao, Jingjing, Tang, Yan, Chen, Hao, Han, Yulong, Song, Mengjia, Huang, Yue, Li, Han, Chen, Yuanyuan, Yang, Chaopin, Yang, Jieying, Wang, Qijing, Li, Yongqiang, He, Jia, Weng, Desheng, Peng, Ruiqing, Xia, Jianchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602592/
https://www.ncbi.nlm.nih.gov/pubmed/34795209
http://dx.doi.org/10.1038/s41419-021-04375-3