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Structural modification of fentanyls for their retrospective identification by gas chromatographic analysis using chloroformate chemistry

The one-step breakdown and derivatization of a panel of nine fentanyls to yield uniquely tagged products that can be detected by Electron Ionization Gas Chromatography-Mass Spectrometry (EI-GC-MS) is presented. The method involves the treatment of the synthetic opioids with 2,2,2-trichloroethoxycarb...

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Detalles Bibliográficos
Autores principales: Valdez, Carlos A., Leif, Roald N., Sanner, Robert D., Corzett, Todd H., Dreyer, Mark L., Mason, Katelyn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602620/
https://www.ncbi.nlm.nih.gov/pubmed/34795347
http://dx.doi.org/10.1038/s41598-021-01896-x