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Jumper enables discontinuous transcript assembly in coronaviruses

Genes in SARS-CoV-2 and other viruses in the order of Nidovirales are expressed by a process of discontinuous transcription which is distinct from alternative splicing in eukaryotes and is mediated by the viral RNA-dependent RNA polymerase. Here, we introduce the DISCONTINUOUS TRANSCRIPT ASSEMBLYpro...

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Detalles Bibliográficos
Autores principales: Sashittal, Palash, Zhang, Chuanyi, Peng, Jian, El-Kebir, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602663/
https://www.ncbi.nlm.nih.gov/pubmed/34795232
http://dx.doi.org/10.1038/s41467-021-26944-y