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A somatic proteoglycan controls Notch-directed germ cell fate

Communication between the soma and germline optimizes germ cell fate programs. Notch receptors are key determinants of germ cell fate but how somatic signals direct Notch-dependent germ cell behavior is undefined. Here we demonstrate that SDN-1 (syndecan-1), a somatic transmembrane proteoglycan, con...

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Detalles Bibliográficos
Autores principales: Gopal, Sandeep, Amran, Aqilah, Elton, Andre, Ng, Leelee, Pocock, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602670/
https://www.ncbi.nlm.nih.gov/pubmed/34795288
http://dx.doi.org/10.1038/s41467-021-27039-4