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Conditional Deletion of Activating Rearranged During Transfection Receptor Tyrosine Kinase Leads to Impairment of Photoreceptor Ribbon Synapses and Disrupted Visual Function in Mice

Purpose: The rearranged during transfection (RET) receptor tyrosine kinase plays a key role in transducing signals related to cell growth and differentiation. Ret mutant mice show abnormal retinal activity and abnormal levels and morphology of bipolar cells, yet die on the 21(st) day after birth as...

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Detalles Bibliográficos
Autores principales: Peng, Wei-Hao, Liao, Meng-Lin, Huang, Wan-Chun, Liu, Pei-Kang, Levi, Sarah R., Tseng, Yun-Ju, Lee, Chia-Ying, Yeh, Lung-Kun, Chen, Kuan-Jen, Chien, Chung-Liang, Wang, Nan-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602685/
https://www.ncbi.nlm.nih.gov/pubmed/34803580
http://dx.doi.org/10.3389/fnins.2021.728905