Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

Candida albicans is the most common cause of fungal sepsis. Inhibition of inflammasome activity confers resistance to polymicrobial and LPS-induced sepsis; however, inflammasome signaling appears to protect against C. albicans infection, so inflammasome inhibitors are not clinically useful for candi...

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Detalles Bibliográficos
Autores principales: Ding, Xionghui, Kambara, Hiroto, Guo, Rongxia, Kanneganti, Apurva, Acosta-Zaldívar, Maikel, Li, Jiajia, Liu, Fei, Bei, Ting, Qi, Wanjun, Xie, Xuemei, Han, Wenli, Liu, Ningning, Zhang, Cunling, Zhang, Xiaoyu, Yu, Hongbo, Zhao, Li, Ma, Fengxia, Köhler, Julia R., Luo, Hongbo R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602704/
https://www.ncbi.nlm.nih.gov/pubmed/34795266
http://dx.doi.org/10.1038/s41467-021-27034-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602704/
https://www.ncbi.nlm.nih.gov/pubmed/34795266
http://dx.doi.org/10.1038/s41467-021-27034-9

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