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redPATH: Reconstructing the Pseudo Development Time of Cell Lineages in Single-cell RNA-seq Data and Applications in Cancer

The recent advancement of single-cell RNA sequencing (scRNA-seq) technologies facilitates the study of cell lineages in developmental processes and cancer. In this study, we developed a computational method, called redPATH, to reconstruct the pseudo developmental time of cell lineages using a consen...

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Detalles Bibliográficos
Autores principales: Xie, Kaikun, Liu, Zehua, Chen, Ning, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602773/
https://www.ncbi.nlm.nih.gov/pubmed/33607293
http://dx.doi.org/10.1016/j.gpb.2020.06.014