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A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation

Polycomb repressive complex 2 (PRC2) is a multi-subunit protein complex mediating the methylation of lysine 27 on histone H3 and playing an important role in transcriptional repression during tumorigenesis and development. Previous studies revealed that both protein-coding and non-coding RNAs could...

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Detalles Bibliográficos
Autores principales: Liao, Meijian, Sun, Xiaolin, Gao, Shoucui, Zhang, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602814/
https://www.ncbi.nlm.nih.gov/pubmed/34804929
http://dx.doi.org/10.3389/fonc.2021.739830