Cargando…
A Class of Protein-Coding RNAs Binds to Polycomb Repressive Complex 2 and Alters Histone Methylation
Polycomb repressive complex 2 (PRC2) is a multi-subunit protein complex mediating the methylation of lysine 27 on histone H3 and playing an important role in transcriptional repression during tumorigenesis and development. Previous studies revealed that both protein-coding and non-coding RNAs could...
Autores principales: | Liao, Meijian, Sun, Xiaolin, Gao, Shoucui, Zhang, Yaou |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602814/ https://www.ncbi.nlm.nih.gov/pubmed/34804929 http://dx.doi.org/10.3389/fonc.2021.739830 |
Ejemplares similares
-
Reduction of H3K27cr Modification During DNA Damage in Colon Cancer
por: Liao, Meijian, et al.
Publicado: (2022) -
Exploring the therapeutic potential of targeting polycomb repressive complex 2 in lung cancer
por: Gao, Min, et al.
Publicado: (2023) -
EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation
por: Mu, Weipeng, et al.
Publicado: (2018) -
PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2
por: Liu, Fan, et al.
Publicado: (2020) -
Promiscuous RNA binding by Polycomb Repressive Complex 2
por: Davidovich, Chen, et al.
Publicado: (2013)