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Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma

The infiltration of tumor-reactive T cells in the tumor site is associated with better survival and immunotherapy response. However, tumor-reactive T cells were often represented by the infiltration of total CD8+ T cells, which was confounded by the presence of bystander T cells. To identify tumor-r...

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Detalles Bibliográficos
Autores principales: Yan, Min, Hu, Jing, Ping, Yanyan, Xu, Liwen, Liao, Gaoming, Jiang, Zedong, Pang, Bo, Sun, Shangqin, Zhang, Yunpeng, Xiao, Yun, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602834/
https://www.ncbi.nlm.nih.gov/pubmed/34804045
http://dx.doi.org/10.3389/fimmu.2021.758288