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SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems

Infection with SARS-CoV-2 triggers the simultaneous activation of innate inflammatory pathways including the complement system and the kallikrein-kinin system (KKS) generating in the process potent vasoactive peptides that contribute to severe acute respiratory syndrome (SARS) and multi-organ failur...

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Detalles Bibliográficos
Autores principales: Savitt, Anne G., Manimala, Samantha, White, Tiara, Fandaros, Marina, Yin, Wei, Duan, Huiquan, Xu, Xin, Geisbrecht, Brian V., Rubenstein, David A., Kaplan, Allen P., Peerschke, Ellinor I., Ghebrehiwet, Berhane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602850/
https://www.ncbi.nlm.nih.gov/pubmed/34804054
http://dx.doi.org/10.3389/fimmu.2021.767347