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SARS-CoV-2 Exacerbates COVID-19 Pathology Through Activation of the Complement and Kinin Systems
Infection with SARS-CoV-2 triggers the simultaneous activation of innate inflammatory pathways including the complement system and the kallikrein-kinin system (KKS) generating in the process potent vasoactive peptides that contribute to severe acute respiratory syndrome (SARS) and multi-organ failur...
Autores principales: | Savitt, Anne G., Manimala, Samantha, White, Tiara, Fandaros, Marina, Yin, Wei, Duan, Huiquan, Xu, Xin, Geisbrecht, Brian V., Rubenstein, David A., Kaplan, Allen P., Peerschke, Ellinor I., Ghebrehiwet, Berhane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602850/ https://www.ncbi.nlm.nih.gov/pubmed/34804054 http://dx.doi.org/10.3389/fimmu.2021.767347 |
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