The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis

The identification of “trained immunity/tolerance” in myeloid cells has changed our perception of the performance of monocytes and macrophages during inflammatory and immune responses. Pemetrexed (PMX) and methotrexate (MTX) are blockers of the one-carbon metabolism (OCM) and commonly used therapeut...

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Detalles Bibliográficos
Autores principales: Fuentelsaz-Romero, Sara, Barrio-Alonso, Celia, García Campos, Raquel, Torres Torresano, Mónica, Muller, Ittai B., Triguero-Martínez, Ana, Nuño, Laura, Villalba, Alejandro, García-Vicuña, Rosario, Jansen, Gerrit, Miranda-Carús, María-Eugenia, González-Álvaro, Isidoro, Puig-Kröger, Amaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602851/
https://www.ncbi.nlm.nih.gov/pubmed/34804067
http://dx.doi.org/10.3389/fimmu.2021.776879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602851/
https://www.ncbi.nlm.nih.gov/pubmed/34804067
http://dx.doi.org/10.3389/fimmu.2021.776879

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