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The Macrophage Reprogramming Ability of Antifolates Reveals Soluble CD14 as a Potential Biomarker for Methotrexate Response in Rheumatoid Arthritis

The identification of “trained immunity/tolerance” in myeloid cells has changed our perception of the performance of monocytes and macrophages during inflammatory and immune responses. Pemetrexed (PMX) and methotrexate (MTX) are blockers of the one-carbon metabolism (OCM) and commonly used therapeut...

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Detalles Bibliográficos
Autores principales:	Fuentelsaz-Romero, Sara, Barrio-Alonso, Celia, García Campos, Raquel, Torres Torresano, Mónica, Muller, Ittai B., Triguero-Martínez, Ana, Nuño, Laura, Villalba, Alejandro, García-Vicuña, Rosario, Jansen, Gerrit, Miranda-Carús, María-Eugenia, González-Álvaro, Isidoro, Puig-Kröger, Amaya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602851/ https://www.ncbi.nlm.nih.gov/pubmed/34804067 http://dx.doi.org/10.3389/fimmu.2021.776879

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