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Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis

It remains poorly defined whether any human miRNAs play protective roles during HIV infection. Here, focusing on a unique cohort of HIV-infected former blood donors, we identified miR-31 (hsa-miR-31) by comparative miRNA profiling as the only miRNA inversely correlating with disease progression. We...

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Detalles Bibliográficos
Autores principales: Zhu, Lingyan, Qiu, Chao, Dai, Lili, Zhang, Linxia, Feng, Meiqi, Yang, Yu, Qiu, Chenli, Zhang, Anli, Huang, Jun, Wang, Ying, Wan, Ying, Zhao, Chen, Wu, Hao, Lyu, Jianxin, Zhang, Xiaoyan, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602903/
https://www.ncbi.nlm.nih.gov/pubmed/34804062
http://dx.doi.org/10.3389/fimmu.2021.771279