Adrenocortical Tumors in Children With Constitutive Chromosome 11p15 Paternal Uniparental Disomy: Implications for Diagnosis and Treatment

Pediatric adrenocortical tumors (ACTs) are rare and heterogeneous. Approximately 50% of children with ACT carry a germline TP53 variant; however, the genetic underpinning of remaining cases has not been elucidated. In patients having germline TP53 variants, loss of maternal chromosome 11 and duplica...

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Detalles Bibliográficos
Autores principales: Pinto, Emilia Modolo, Rodriguez-Galindo, Carlos, Lam, Catherine G., Ruiz, Robert E., Zambetti, Gerard P., Ribeiro, Raul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602920/
https://www.ncbi.nlm.nih.gov/pubmed/34803919
http://dx.doi.org/10.3389/fendo.2021.756523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602920/
https://www.ncbi.nlm.nih.gov/pubmed/34803919
http://dx.doi.org/10.3389/fendo.2021.756523

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