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A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation

Adenosine-to-inosine RNA editing and the catalyzing enzyme adenosine deaminase are both essential for hematopoietic development and differentiation. However, the RNA editome during hematopoiesis and the underlying mechanisms are poorly defined. Here, we sorted 12 murine adult hematopoietic cell popu...

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Detalles Bibliográficos
Autores principales: Wang, Fengjiao, He, Jiahuan, Liu, Siqi, Gao, Ai, Yang, Liu, Sun, Guohuan, Ding, Wanqiu, Li, Chuan-Yun, Gou, Fanglin, He, Manman, Wang, Fang, Wang, Xiaoshuang, Zhao, Xiangnan, Zhu, Ping, Hao, Sha, Ma, Yanni, Cheng, Hui, Yu, Jia, Cheng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8602937/
https://www.ncbi.nlm.nih.gov/pubmed/34388251
http://dx.doi.org/10.1182/blood.2021011314