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Modular assembly and encoding strategies for dual-display DNA-encoded chemical libraries

DNA-encoded chemical libraries (DELs) are increasingly being used for the discovery of protein ligands and can be constructed displaying either one or two molecules at the extremities of the two complementary DNA strands. Here, we describe that DELs, featuring the simultaneous display of two molecul...

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Detalles Bibliográficos
Autores principales: Oehler, Sebastian, Plais, Louise, Bassi, Gabriele, Neri, Dario, Scheuermann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603192/
https://www.ncbi.nlm.nih.gov/pubmed/34730584
http://dx.doi.org/10.1039/d1cc04306d