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Critical roles of a housekeeping sortase of probiotic Bifidobacterium bifidum in bacterium–host cell crosstalk

Bifidobacterium bifidum YIT 10347 (BF-1) is adhesive in vitro. Here we studied the molecular aspects of the BF-1 adhesion process. We identified and characterized non-adhesive mutants and found that a class E housekeeping sortase was critical for the adhesion to mucin. These mutants were significant...

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Detalles Bibliográficos
Autores principales: Ishikawa, Eiji, Yamada, Tetsuya, Yamaji, Kazuaki, Serata, Masaki, Fujii, Daichi, Umesaki, Yoshinori, Tsuji, Hirokazu, Nomoto, Koji, Ito, Masahiro, Okada, Nobuhiko, Nagaoka, Masato, Gomi, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603203/
https://www.ncbi.nlm.nih.gov/pubmed/34825137
http://dx.doi.org/10.1016/j.isci.2021.103363