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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition

Analysis of nucleotide variants is a cornerstone of cancer medicine. Although only 2% of the genomic sequence is protein coding, mutations occurring in these regions have the potential to influence protein structure or modification status and may have severe impact on disease aetiology. Proteogenomi...

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Detalles Bibliográficos
Autores principales: Schmitt, Marisa, Sinnberg, Tobias, Bratl, Katrin, Zittlau, Katharina, Garbe, Claus, Macek, Boris, Nalpas, Nicolas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603206/
https://www.ncbi.nlm.nih.gov/pubmed/34673281
http://dx.doi.org/10.1016/j.mcpro.2021.100163