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For whom the T cells troll? Bispecific T-cell engagers in glioblastoma

Glioblastoma is the the most common primary brain tumor in adults. Onset of disease is followed by a uniformly lethal prognosis and dismal overall survival. While immunotherapies have revolutionized treatment in other difficult-to-treat cancers, these have failed to demonstrate significant clinical...

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Detalles Bibliográficos
Autores principales: Singh, Kirit, Hotchkiss, Kelly M, Mohan, Aditya A, Reedy, Jessica L, Sampson, John H, Khasraw, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603282/
https://www.ncbi.nlm.nih.gov/pubmed/34795007
http://dx.doi.org/10.1136/jitc-2021-003679