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Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness

The diacylglycerol kinases (DGKs) are a family of enzymes responsible for the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). In addition to their primary function in lipid metabolism, DGKs have recently been identified as potential therapeutic targets in multiple cancers, including gl...

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Detalles Bibliográficos
Autores principales: Manigat, Laryssa C., Granade, Mitchell E., Taori, Suchet, Miller, Charlotte Anne, Vass, Luke R., Zhong, Xiao-Ping, Harris, Thurl E., Purow, Benjamin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603347/
https://www.ncbi.nlm.nih.gov/pubmed/34804012
http://dx.doi.org/10.3389/fimmu.2021.722469