Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis

The cysteine protease inhibitor Cystatin C (CST3) is highly expressed in the brains of multiple sclerosis (MS) patients and C57BL/6J mice with experimental autoimmune encephalomyelitis (EAE; a model of MS), but its roles in the diseases are unknown. Here, we show that CST3 plays a detrimental functi...

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Detalles Bibliográficos
Autores principales: Hoghooghi, Vahid, Palmer, Alexandra L., Frederick, Ariana, Jiang, Yulan, Merkens, Jessica E., Balakrishnan, Anjali, Finlay, Trisha M., Grubb, Anders, Levy, Efrat, Gordon, Paul, Jirik, Frank R., Nguyen, Minh Dang, Schuurmans, Carol, Visser, Frank, Dunn, Shannon E., Ousman, Shalina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603395/
https://www.ncbi.nlm.nih.gov/pubmed/33027652
http://dx.doi.org/10.1016/j.celrep.2020.108236

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603395/
https://www.ncbi.nlm.nih.gov/pubmed/33027652
http://dx.doi.org/10.1016/j.celrep.2020.108236

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