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Protocol: Pentoxifylline optimal dose finding trial in preterm neonates with suspected late onset sepsis (PTX-trial)

BACKGROUND: Late onset sepsis is a leading cause of death and morbidity in preterm infants. Despite optimal antibiotic treatment, sepsis related mortality and morbidity is still high. Pentoxifylline (PTX) is a methylxanthine with promising immunomodulatory properties, which can be used as an additio...

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Detalles Bibliográficos
Autores principales: Kurul, Serife, Taal, H. Rob, Flint, Robert B., Mazela, Jan, Reiss, Irwin K. M., Allegaert, Karel, Simons, Sinno H. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603542/
https://www.ncbi.nlm.nih.gov/pubmed/34794420
http://dx.doi.org/10.1186/s12887-021-02975-8