CD4+ effector T cells accelerate Alzheimer’s disease in mice

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by pathological deposition of misfolded self-protein amyloid beta (Aβ) which in kind facilitates tau aggregation and neurodegeneration. Neuroinflammation is accepted as a key disease driver caused by innat...

Descripción completa

Detalles Bibliográficos
Autores principales: Machhi, Jatin, Yeapuri, Pravin, Lu, Yaman, Foster, Emma, Chikhale, Rupesh, Herskovitz, Jonathan, Namminga, Krista L., Olson, Katherine E., Abdelmoaty, Mai Mohamed, Gao, Ju, Quadros, Rolen M., Kiyota, Tomomi, Jingjing, Liang, Kevadiya, Bhavesh D., Wang, Xinglong, Liu, Yutong, Poluektova, Larisa Y., Gurumurthy, Channabasavaiah B., Mosley, R. Lee, Gendelman, Howard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603581/
https://www.ncbi.nlm.nih.gov/pubmed/34798897
http://dx.doi.org/10.1186/s12974-021-02308-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603581/
https://www.ncbi.nlm.nih.gov/pubmed/34798897
http://dx.doi.org/10.1186/s12974-021-02308-7

Ejemplares similares