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Mendelian randomisation with coarsened exposures
A key assumption in Mendelian randomisation is that the relationship between the genetic instruments and the outcome is fully mediated by the exposure, known as the exclusion restriction assumption. However, in epidemiological studies, the exposure is often a coarsened approximation to some latent c...
Autores principales: | Tudball, Matthew J., Bowden, Jack, Hughes, Rachael A., Ly, Amanda, Munafò, Marcus R., Tilling, Kate, Zhao, Qingyuan, Davey Smith, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603937/ https://www.ncbi.nlm.nih.gov/pubmed/33527565 http://dx.doi.org/10.1002/gepi.22376 |
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