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AIM2 forms a complex with Pyrin and ZBP1 to drive PANoptosis and host defense

Inflammasomes are important sentinels of innate immune defense, sensing pathogens and inducing cell death in infected cells(1). There are several inflammasome sensors that each detect and respond to specific pathogen- and damage-associated molecular patterns (PAMPs and DAMPs)(1). In contrast to this...

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Detalles Bibliográficos
Autores principales: Lee, SangJoon, Karki, Rajendra, Wang, Yaqiu, Nguyen, Lam Nhat, Kalathur, Ravi C., Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603942/
https://www.ncbi.nlm.nih.gov/pubmed/34471287
http://dx.doi.org/10.1038/s41586-021-03875-8