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cGAS/STING: novel perspectives of the classic pathway

Cyclic GMP-AMP (cGAMP) synthase (cGAS) is a cytosolic DNA sensor and innate immune response initiator. Binding with exogenous or endogenous nucleic acids, cGAS activates its downstream adaptor, stimulator of interferon genes (STING). STING then triggers protective immune to enable the elimination of...

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Detalles Bibliográficos
Autores principales: Gao, Menghui, He, Yuchen, Tang, Haosheng, Chen, Xiangyu, Liu, Shuang, Tao, Yongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8603984/
https://www.ncbi.nlm.nih.gov/pubmed/35006429
http://dx.doi.org/10.1186/s43556-020-00006-z