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Viperin is anti-viral in vitro but is dispensable for restricting dengue virus replication or induction of innate and inflammatory responses in vivo

Viperin has antiviral function against many viruses, including dengue virus (DENV), when studied in cells in culture. Here, the antiviral actions of viperin were defined both in vitro and in a mouse in vivo model of DENV infection. Murine embryonic fibroblasts (MEFs) derived from mice lacking viperi...

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Detalles Bibliográficos
Autores principales: Al Shujairi, Wisam-Hamzah, Kris, Luke P., van der Hoek, Kylie, Cowell, Evangeline, Bracho-Granado, Gustavo, Woodgate, Tahlia, Beard, Michael R., Carr, Jillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604189/
https://www.ncbi.nlm.nih.gov/pubmed/34665110
http://dx.doi.org/10.1099/jgv.0.001669