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Viperin is anti-viral in vitro but is dispensable for restricting dengue virus replication or induction of innate and inflammatory responses in vivo
Viperin has antiviral function against many viruses, including dengue virus (DENV), when studied in cells in culture. Here, the antiviral actions of viperin were defined both in vitro and in a mouse in vivo model of DENV infection. Murine embryonic fibroblasts (MEFs) derived from mice lacking viperi...
Autores principales: | Al Shujairi, Wisam-Hamzah, Kris, Luke P., van der Hoek, Kylie, Cowell, Evangeline, Bracho-Granado, Gustavo, Woodgate, Tahlia, Beard, Michael R., Carr, Jillian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604189/ https://www.ncbi.nlm.nih.gov/pubmed/34665110 http://dx.doi.org/10.1099/jgv.0.001669 |
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