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A first‐in‐human study of KMRC011, a potential treatment for acute radiation syndrome, to explore tolerability, pharmacokinetics, and pharmacodynamics

KMRC011 is a novel Toll‐like receptor 5 agonist under development as a treatment for acute radiation syndrome (ARS). The aim of this first‐in‐human study was to investigate the tolerability, pharmacokinetics, and pharmacodynamics of a single intramuscular dose of KMRC011 in healthy subjects. A rando...

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Detalles Bibliográficos
Autores principales: Yang, Eunsol, Choi, Hyejung, Park, Jin‐Sol, Noh, Young‐Woock, Choi, Chi‐Min, Lee, Woo‐Jong, Ko, Jae‐Wook, Kim, Jungryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604209/
https://www.ncbi.nlm.nih.gov/pubmed/34080313
http://dx.doi.org/10.1111/cts.13073