Cargando…

Pharmacokinetics of daridorexant, a dual orexin receptor antagonist, are not affected by renal impairment

The aim of this study was to evaluate the impact of renal impairment on the pharmacokinetics (PKs), safety, and tolerability of daridorexant, a dual orexin receptor antagonist intended for the treatment of insomnia. A single‐center, open‐label study evaluated the PKs of daridorexant in patients with...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, Benjamin, Muehlan, Clemens, Klein, Gernot, Dingemanse, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604215/
https://www.ncbi.nlm.nih.gov/pubmed/34121345
http://dx.doi.org/10.1111/cts.13079