REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics

REGN1908‐1909, a 1:1 cocktail of two fully human IgG(4) monoclonal antibodies (mAbs), REGN1908 and REGN1909, is being evaluated for treatment of cat allergy. Both REGN1908 and REGN1909 bind to the dominant cat allergen, Fel d 1. Adults with cat allergy confirmed by skin prick test (SPT) were randomi...

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Detalles Bibliográficos
Autores principales: Kamal, Mohamed A., Dingman, Robert, Wang, Claire Q., Lai, Ching‐Ha, Rajadhyaksha, Manoj, DeVeaux, Michelle, Orengo, Jamie M., Radin, Allen, Davis, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604232/
https://www.ncbi.nlm.nih.gov/pubmed/34437752
http://dx.doi.org/10.1111/cts.13112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604232/
https://www.ncbi.nlm.nih.gov/pubmed/34437752
http://dx.doi.org/10.1111/cts.13112

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