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Oral and intravenous pharmacokinetics of metformin with and without oral codeine intake in healthy subjects: A cross‐over study

The aim of the study was to investigate if there is a clinically relevant drug interaction between metformin and codeine. Volunteers were randomized to receive on four separate occasions: (A) orally administered metformin (1 g), (B) intravenously administered metformin (0.5 g), (C) five doses of tab...

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Detalles Bibliográficos
Autores principales: Kuhlmann, Ida, Nøddebo Nyrup, Amanda, Bjerregaard Stage, Tore, Hougaard Christensen, Mette Marie, Korshøj Bergmann, Troels, Damkier, Per, Nielsen, Flemming, Højlund, Kurt, Brøsen, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604249/
https://www.ncbi.nlm.nih.gov/pubmed/34268884
http://dx.doi.org/10.1111/cts.13107