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Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress

In haploid budding yeast, evolutionary adaptation to constitutive DNA replication stress alters three genome maintenance modules: DNA replication, the DNA damage checkpoint, and sister chromatid cohesion. We asked how these trajectories depend on genomic features by comparing the adaptation in three...

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Detalles Bibliográficos
Autores principales: Fumasoni, Marco, Murray, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604288/
https://www.ncbi.nlm.nih.gov/pubmed/34752451
http://dx.doi.org/10.1371/journal.pgen.1009875