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Ploidy and recombination proficiency shape the evolutionary adaptation to constitutive DNA replication stress
In haploid budding yeast, evolutionary adaptation to constitutive DNA replication stress alters three genome maintenance modules: DNA replication, the DNA damage checkpoint, and sister chromatid cohesion. We asked how these trajectories depend on genomic features by comparing the adaptation in three...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604288/ https://www.ncbi.nlm.nih.gov/pubmed/34752451 http://dx.doi.org/10.1371/journal.pgen.1009875 |