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Spatial protein heterogeneity analysis in frozen tissues to evaluate tumor heterogeneity

A new workflow for protein-based tumor heterogeneity probing in tissues is here presented. Tumor heterogeneity is believed to be key for therapy failure and differences in prognosis in cancer patients. Comprehending tumor heterogeneity, especially at the protein level, is critical for tracking tumor...

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Detalles Bibliográficos
Autores principales: Fomitcheva-Khartchenko, Anna, Rapsomaniki, Maria Anna, Sobottka, Bettina, Schraml, Peter, Kaigala, Govind V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604290/
https://www.ncbi.nlm.nih.gov/pubmed/34797831
http://dx.doi.org/10.1371/journal.pone.0259332