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Discovery of an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes

Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell. There is a growing demand for practical and accessible tools for dissecting the role of the actin cytoskeleton in cellular function, and the discovery of a new actin-binding small mole...

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Detalles Bibliográficos
Autores principales: Takagi, Takeru, Ueno, Tasuku, Ikawa, Keisuke, Asanuma, Daisuke, Nomura, Yusuke, Uno, Shin-nosuke, Komatsu, Toru, Kamiya, Mako, Hanaoka, Kenjiro, Okimura, Chika, Iwadate, Yoshiaki, Hirose, Kenzo, Nagano, Tetsuo, Sugimura, Kaoru, Urano, Yasuteru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604405/
https://www.ncbi.nlm.nih.gov/pubmed/34797716
http://dx.doi.org/10.1126/sciadv.abg8585