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Discovery of an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell. There is a growing demand for practical and accessible tools for dissecting the role of the actin cytoskeleton in cellular function, and the discovery of a new actin-binding small mole...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604405/ https://www.ncbi.nlm.nih.gov/pubmed/34797716 http://dx.doi.org/10.1126/sciadv.abg8585 |