Quantitative spatial and temporal assessment of regulatory element activity in zebrafish

Mutations or genetic variation in noncoding regions of the genome harbouring cis-regulatory elements (CREs), or enhancers, have been widely implicated in human disease and disease risk. However, our ability to assay the impact of these DNA sequence changes on enhancer activity is currently very limi...

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Detalles Bibliográficos
Autores principales: Bhatia, Shipra, Kleinjan, Dirk Jan, Uttley, Kirsty, Mann, Anita, Dellepiane, Nefeli, Bickmore, Wendy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604437/
https://www.ncbi.nlm.nih.gov/pubmed/34796872
http://dx.doi.org/10.7554/eLife.65601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604437/
https://www.ncbi.nlm.nih.gov/pubmed/34796872
http://dx.doi.org/10.7554/eLife.65601

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