NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells

Nuclear pore complexes (NPC) regulate molecular traffics on nuclear envelope, which plays crucial roles during cell fate specification and diseases. The viral accessory protein NSP9 of SARS-CoV-2 is reported to interact with nucleoporin 62 (NUP62), a structural component of the NPC, but its biologic...

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Detalles Bibliográficos
Autores principales: Makiyama, Kei, Hazawa, Masaharu, Kobayashi, Akiko, Lim, Keesiang, Voon, Dominic C., Wong, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604569/
https://www.ncbi.nlm.nih.gov/pubmed/34844119
http://dx.doi.org/10.1016/j.bbrc.2021.11.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604569/
https://www.ncbi.nlm.nih.gov/pubmed/34844119
http://dx.doi.org/10.1016/j.bbrc.2021.11.046

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