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NSP9 of SARS-CoV-2 attenuates nuclear transport by hampering nucleoporin 62 dynamics and functions in host cells
Nuclear pore complexes (NPC) regulate molecular traffics on nuclear envelope, which plays crucial roles during cell fate specification and diseases. The viral accessory protein NSP9 of SARS-CoV-2 is reported to interact with nucleoporin 62 (NUP62), a structural component of the NPC, but its biologic...
Autores principales: | Makiyama, Kei, Hazawa, Masaharu, Kobayashi, Akiko, Lim, Keesiang, Voon, Dominic C., Wong, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604569/ https://www.ncbi.nlm.nih.gov/pubmed/34844119 http://dx.doi.org/10.1016/j.bbrc.2021.11.046 |
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