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Melatonin Ameliorates Valproic Acid-Induced Neurogenesis Impairment: The Role of Oxidative Stress in Adult Rats

BACKGROUND: Valproic acid (anticonvulsant medication) has been found to inhibit histone deacetylase activity and suppress hippocampal neurogenesis, which causes memory impairment in both humans and rodents. The neurohormone melatonin, which regulates mammalian seasonal and circadian physiology, has...

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Detalles Bibliográficos
Autores principales: Aranarochana, Anusara, Sirichoat, Apiwat, Pannangrong, Wanassanun, Wigmore, Peter, Welbat, Jariya Umka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604576/
https://www.ncbi.nlm.nih.gov/pubmed/34804374
http://dx.doi.org/10.1155/2021/9997582