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Lidocaine Alleviates Sepsis-Induced Acute Lung Injury in Mice by Suppressing Tissue Factor and Matrix Metalloproteinase-2/9

Acute lung injury (ALI) is one of the fatal symptoms of sepsis. However, there were no effective clinical treatments. TF accumulation-induced fibrin deposit formations and coagulation abnormalities in pulmonary vessels contribute to the lethality of ALI. Suppressor of cytokine signaling 3 (SOCS3) ac...

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Detalles Bibliográficos
Autores principales: Zheng, Binbin, Yang, Hongbo, Zhang, Jianan, Wang, Xueli, Sun, Hao, Hu, Fan, Li, Qian, Jiang, Liping, Su, Yue, Peng, Qilin, Tang, Yulin, Liu, Wen-Tao, He, Xueming, Fan, Yixin, Zhu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604580/
https://www.ncbi.nlm.nih.gov/pubmed/34804364
http://dx.doi.org/10.1155/2021/3827501