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IL-33/ST2 Axis Deficiency Exacerbates Hepatic Pathology by Regulating Treg and Th17 Cells in Murine Schistosomiasis Japonica

PURPOSE: Schistosoma japonicum-infected IL-33 and ST2 gene deficiency (IL-33(−/−) and ST2(−/−), respectively) mice were used to explore the role of the IL-33/ST2 axis in liver pathology targeting regulatory T cells (Treg)/T helper 17 cells (Th17). MATERIALS AND METHODS: Each mouse was infected percu...

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Detalles Bibliográficos
Autores principales: Bai, Yang, Guan, Fei, Zhu, Feifan, Jiang, Chunjie, Xu, XiaoXiao, Zheng, Fang, Liu, Wenqi, Lei, Jiahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604654/
https://www.ncbi.nlm.nih.gov/pubmed/34815688
http://dx.doi.org/10.2147/JIR.S336404