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Synergistic alterations in the multilevel chromatin structure anchor dysregulated genes in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive form of lung cancer that uniquely changes the chromosomal structure, although the basis of aberrant gene expression in SCLC remains largely unclear. Topologically associated domains (TADs) are structural and functional units of the human genome. Genetic...

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Detalles Bibliográficos
Autores principales: Guo, Dan, Xie, Qiu, Jiang, Shuai, Xie, Ting, Li, Yaru, Huang, Xin, Li, Fangyuan, Wang, Tingting, Sun, Jian, Wang, Anqi, Zhang, Zixin, Li, Hao, Bo, Xiaochen, Chen, Hebing, Liang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604672/
https://www.ncbi.nlm.nih.gov/pubmed/34849199
http://dx.doi.org/10.1016/j.csbj.2021.11.003