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Synergistic alterations in the multilevel chromatin structure anchor dysregulated genes in small cell lung cancer
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that uniquely changes the chromosomal structure, although the basis of aberrant gene expression in SCLC remains largely unclear. Topologically associated domains (TADs) are structural and functional units of the human genome. Genetic...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604672/ https://www.ncbi.nlm.nih.gov/pubmed/34849199 http://dx.doi.org/10.1016/j.csbj.2021.11.003 |