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The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30

The prevalence of nonalcoholic steatohepatitis (NASH) caused by estrogen deficiency increased sharply in recent decades and has become a major threat to liver health in postmenopausal women. There is no effective strategy to control the incidence and development of NASH. Dehydroepiandrosterone (DHEA...

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Detalles Bibliográficos
Autores principales: Li, Longlong, Wang, Hongjun, Yao, Yao, Cao, Ji, Jiang, Zhihao, Yan, Weiyuan, Chu, Xu, Li, Qian, Lu, Miaomiao, Ma, Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604675/
https://www.ncbi.nlm.nih.gov/pubmed/34781165
http://dx.doi.org/10.1016/j.redox.2021.102187