Cargando…
The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30
The prevalence of nonalcoholic steatohepatitis (NASH) caused by estrogen deficiency increased sharply in recent decades and has become a major threat to liver health in postmenopausal women. There is no effective strategy to control the incidence and development of NASH. Dehydroepiandrosterone (DHEA...
Autores principales: | Li, Longlong, Wang, Hongjun, Yao, Yao, Cao, Ji, Jiang, Zhihao, Yan, Weiyuan, Chu, Xu, Li, Qian, Lu, Miaomiao, Ma, Haitian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604675/ https://www.ncbi.nlm.nih.gov/pubmed/34781165 http://dx.doi.org/10.1016/j.redox.2021.102187 |
Ejemplares similares
-
Dehydroepiandrosterone alleviates oleic acid-induced lipid metabolism disorders through activation of AMPK-mTOR signal pathway in primary chicken hepatocytes
por: Yao, Yao, et al.
Publicado: (2022) -
Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages
por: Cao, Ji, et al.
Publicado: (2022) -
Dehydroepiandrosterone Prevents H(2)O(2)-Induced BRL-3A Cell Oxidative Damage through Activation of PI3K/Akt Pathways rather than MAPK Pathways
por: Li, Longlong, et al.
Publicado: (2019) -
Genistein alleviates chronic heat stress-induced lipid metabolism disorder and mitochondrial energetic dysfunction by activating the GPR30-AMPK-PGC-1α signaling pathways in the livers of broiler chickens
por: Li, Longlong, et al.
Publicado: (2023) -
4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes
por: Chu, Xu, et al.
Publicado: (2022)