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Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy

SARS-CoV-2 messenger RNA vaccination in healthy individuals generates immune protection against COVID-19. However, little is known about SARS-CoV-2 mRNA vaccine-induced responses in immunosuppressed patients. We investigated induction of antigen-specific antibody, B cell and T cell responses longitu...

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Detalles Bibliográficos
Autores principales: Apostolidis, Sokratis A., Kakara, Mihir, Painter, Mark M., Goel, Rishi R., Mathew, Divij, Lenzi, Kerry, Rezk, Ayman, Patterson, Kristina R., Espinoza, Diego A., Kadri, Jessy C., Markowitz, Daniel M., E. Markowitz, Clyde, Mexhitaj, Ina, Jacobs, Dina, Babb, Allison, Betts, Michael R., Prak, Eline T. Luning, Weiskopf, Daniela, Grifoni, Alba, Lundgreen, Kendall A., Gouma, Sigrid, Sette, Alessandro, Bates, Paul, Hensley, Scott E., Greenplate, Allison R., Wherry, E. John, Li, Rui, Bar-Or, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604727/
https://www.ncbi.nlm.nih.gov/pubmed/34522051
http://dx.doi.org/10.1038/s41591-021-01507-2