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Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Cholecystokinin A receptor (CCK(A)R) belongs to family A G-protein-coupled receptors and regulates nutrient homeostasis upon stimulation by cholecystokinin (CCK). It is an attractive drug target for gastrointestinal and metabolic diseases. One distinguishing feature of CCK(A)R is its ability to inte...

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Detalles Bibliográficos
Autores principales: Liu, Qiufeng, Yang, Dehua, Zhuang, Youwen, Croll, Tristan I., Cai, Xiaoqing, Dai, Antao, He, Xinheng, Duan, Jia, Yin, Wanchao, Ye, Chenyu, Zhou, Fulai, Wu, Beili, Zhao, Qiang, Xu, H. Eric, Wang, Ming-Wei, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604728/
https://www.ncbi.nlm.nih.gov/pubmed/34556862
http://dx.doi.org/10.1038/s41589-021-00841-3